Claim: Alcohol exposure during pregnancy affects multiple generations

Nonsense. Lamarckism masquerading as “epigenetics.”

In any event, lab rats aren’t little people.

The media release is below.

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Alcohol exposure during pregnancy affects multiple generations
BINGHAMTON UNIVERSITY

BINGHAMTON, NY – When a mother drinks alcohol during pregnancy, even a small dose, she can increase the chances that the next three generations may develop alcoholism, according to a new study from Binghamton University.

A research team led by Nicole Cameron, assistant professor of psychology at Binghamton University, was the first to investigate the effects of alcohol consumption during pregnancy on alcohol-related behavior (consumption and sensitivity to the effect of alcohol) on generations that were not directly exposed to alcohol in the uterus during the pregnancy.

Pregnant rats received the equivalent of one glass of wine, four days in a row, at gestational days 17-20, the equivalent of the second trimester in humans. Juvenile male and female offspring were then tested for water or alcohol consumption. Adolescent males were tested for sensitivity to alcohol by injecting them with a high-alcohol dose, which made them unresponsive (drunk on their back), and measuring the time it took them to recover their senses (back on their four paws). The results suggest that if a mother drinks during pregnancy, even just a little bit, she increases the risk that her progeny will become alcoholic.

“Our findings show that in the rat, when a mother consumes the equivalent of one glass of wine four times during the pregnancy, her offspring and grand-offspring, up to the third generation, show increased alcohol preference and less sensitivity to alcohol,” said Cameron. “Thus, the offspring are more likely to develop alcoholism. This paper is the first to demonstrate trans-generational effects of alcohol consumption during pregnancy on alcohol-related behavior in offspring.”

To date, no study has shown a transgenerational effect of prenatal ethanol exposure on ethanol consumption in the second or third generation. Other research investigated the effects of alcohol exposure during pregnancy studied the effects only on the fetuses directly exposed or the effects on cellular activity over multiple generations, but never alcohol-related behaviors over multiple generations.

Cameron and her team recently received a National Institute on Alcohol Abuse and Alcoholism grant to continue the research on the transgenerational effects of gestational alcohol exposure.

“We now need to identify how this effect is pass through multiple generations by investigating the effects alcohol has on the genome and epigenome (molecules that control gene translation),” said Cameron.

This research was conducted in collaboration with Michael Nizhnikov from South Connecticut University.

The study, “Trans-generational transmission of the effect of gestational ethanol exposure on ethanol use-related behavior,” was published Feb. 15 in Alcoholism: Clinical and Experimental Research.

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4 thoughts on “Claim: Alcohol exposure during pregnancy affects multiple generations”

  1. Sean, yes, Wealth and Poverty, by George Gilder. However, nothing has been done on exposure of fuzzy subject academia to government largesse, and the subsequent loss of morals, judgment, honesty, and brain tissue.

  2. so, did they expose or not expose the progenitors of the future generations prior to conception of their progeny? I mean, did they expose the children and THEN let them have children, or did they leave at least one pair unexposed to alcohol prior to the conception and birth of the next generation?

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