Coffee prevents endometrial cancer?

News from the magical food front.

From an American Association of Cancer Research media release:

Coffee may protect against endometrial cancer

PHILADELPHIA — Long-term coffee consumption may be associated with a reduced risk for endometrial cancer, according to a recent study in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Edward Giovannucci, M.D., Sc.D., professor of nutrition and epidemiology at the Harvard School of Public Health, said coffee is emerging as a protective agent in cancers that are linked to obesity, estrogen and insulin.

“Coffee has already been shown to be protective against diabetes due to its effect on insulin,” said Giovannucci, a senior researcher on the study. “So we hypothesized that we’d see a reduction in some cancers as well.”

Giovannucci, along with Youjin Je, a doctoral candidate in his lab, and colleagues observed cumulative coffee intake in relation to endometrial cancer in 67,470 women who enrolled in the Nurses’ Health Study.

During the course of 26 years of follow-up, researchers documented 672 cases of endometrial cancer.

Drinking more than four cups of coffee per day was linked with a 25 percent reduced risk for endometrial cancer. Drinking between two and three cups per day was linked with a 7 percent reduced risk.

A similar link was seen in decaffeinated coffee, where drinking more than two cups per day was linked with a 22 percent reduced risk for endometrial cancer.

Giovannucci said he hopes this study will lead to further inquiries about the effect of coffee on cancer because in this and similar studies, coffee intake is self-selected and not randomized.

“Coffee has long been linked with smoking, and if you drink coffee and smoke, the positive effects of coffee are going to be more than outweighed by the negative effects of smoking,” said Giovannucci. “However, laboratory testing has found that coffee has much more antioxidants than most vegetables and fruits.”

This study provides no evidence that coffee drinking protects against endometrial cancer. The correlations are in the statistical noise range, the exposure data is self-reported and uncertain, and no one knows what causes endometrial cancer.

The notion that magical antioxidants in coffee are scavenging cancer-causing free-radicals remains about as credible as scrubbing bubbles.

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2 responses to “Coffee prevents endometrial cancer?

  1. Are you sure it is not statistically significant. It would be too bad I can’t use cancer prevention and insulin regulation along with my other reasons for more than 4 cups of coffee per day. Oh, well, guess I’ll have to fall back on the fact that the time I spend reading environmental regulations and the like requires strong drink in large amounts. (PS. The stuff I have to read would be considered cruel and unusual and against the Geneva conventions if forced on POW’s)

    I suppose I could use the excuse that I just happen to like coffee. But where is the fun in that?

  2. This is good news for coffee drinkers. It’s time for another cup to celebrate it.

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